1. Prevalence, Predictors, and Moderators of Relapse in Severe Mental Disorders: Evidence from Ndera Neuropsychiatric Teaching Hospital, Rwanda

C. Nkubili, P. Uwamungu, S. Ntirenganya, E.F. Twizeyimana, E. Kagabo, E. Ntakiyisumba, J.C. Musabyimana, M. Nshimiyimana, A. Mbabazi, E. Niyonsaba, B. Uwamwezi, F. U. Baho, F. Sebera, F. Nyirandamutsa, J. Niyonsenga

• Relapse remains a significant challenge in the management of severe mental disorders, particularly in low-resource settings. This cross-sectional study conducted among outpatients at Ndera Neuropsychiatric Teaching Hospital estimated relapse prevalence and examined associated factors, including medication adherence, self-stigma, psychological well-being, and disorder type.

2. Association of depression and epilepsy in Rwanda: A prospective longitudinal study

Fidele Sebera, Peter Dedeken, Ieme Garrez, Josiane Umwiringirwa, Tim Leers, Jean-Pierre Ndacyayisenga, Sylvestre Mutungirehe, Arlene Ndayisenga, Odette Niyonzima, Georgette Umuhoza, Dirk E. Teuwen & Paul A.M.J.Boon

• Depression is the most common psychiatric comorbidity for persons living with epilepsy. In Rwanda, the prevalence of epilepsy and depression are high, with 4,9% and 13.0% respectively. This prospective interventional study aimed to determine the prevalence and incidence of depression and the outcome of persons living with epilepsy (PwE) with depression attending the outpatient neurology department of a tertiary center.

3. Effectiveness of community health workers on identification and mobilization of persons living with epilepsy in rural Rwanda using a validated screening tool

Fidele Sebera, Peter Dedeken, Jeannine Kayirangwa, Josiane Umwiringirwa, Delphine Kajeneza, Nicole Alves dos Reis, Tim Leers, Dirk E. Teuwen & Paul A. J. M. Boon

• Engagement and training of community health workers (CHWs) have demonstrated their value in different conditions. Despite repeat epilepsy trainings of CHWs in Northern Rwanda, the treatment gap remained high. The study hypothesized that effectiveness of CHWs on mobilization of patients living with epilepsy (PwE) could be improved using a validated tool for epilepsy screening.

4. Addressing the treatment gap and societal impact of epilepsy in Rwanda — Results of a survey conducted in 2005,  Sebera et al and subsequent action

Fidèle Sebera, Naasson Munyandamutsa, Dirk E. Teuwen, Ibrahim Pierre Ndiaye, Amadou Gallo Diop, Azita Tofighy Paul Boon & Peter Dedeken

• This study, supported by the Rwandan Ministry of Health and the World Health Organization, was conducted in 2005 to determine the prevalence of epilepsy and its sociocultural perception in Rwanda, as well as epilepsy-related knowledge and practices of health-care professionals (HCPs).

5. Mortality of all causes and sudden unexplained death in epilepsy (SUDEP) in a cohort of 235 persons living with epilepsy in Rwanda using WHO Verbal Autopsy Questionnaire

Fidèle Sebera, Béni H. Uwacu, Wellars Nsanzabaganwa, Josiane Umwiringirwa, Peter Dedeken, Dirk E. Teuwen & Paul A. J. M. Boon

• Mortality in persons living with epilepsy (PwE) is 1.6–9.3-fold higher than in the general population. Mortality from definite/probable Sudden Unexpected Death in EPilepsy (SUDEP) is estimated at 1.2 per 1000 person-years. The study reports mortality and SUDEP rate in a cohort of Rwandan PwE.

6. Clinical study to assess the treatment of Schizophrenia with Paliperidone Palmitate in Healthcare settings

• The ongoing research is being carried out by Dr Rutakayile Bizoza. Sponsored by Janssen Pharmaceutica NV, the research is being carried out in Neuro-Psychiatric Teaching Hospital CARAES Ndera and other 4 health institutions in Rwanda, with target population of 100.